Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes
نویسندگان
چکیده
منابع مشابه
Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes
The adverse effects to humans and environment of only few chemicals are well known. Absorption, distribution, metabolism, and excretion (ADME) are the steps of pharmaco/toxicokinetics that determine the internal dose of chemicals to which the organism is exposed. Of all the xenobiotic-metabolizing enzymes, the cytochrome P450 (CYP) enzymes are the most important due to their abundance and versa...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2015
ISSN: 1663-9812
DOI: 10.3389/fphar.2015.00123